Josh Wolfe and Brett McGurk, Partners at Lux Capital, a $5 billion venture capital firm that specializes in emerging science and technology companies that turn sci-fi into sci-fact. Josh co-founded Lux and is a repeat past guest on the show. His first appearance from 2018 discusses his story, including phrases: ‘chips in shoulders put chips in pockets,’ ‘failure comes from a failure to imagine failure,’ and ‘directional arrows of progress.’

Brett joined Lux last year, following a 20-year career in public service where he advised four U.S. presidents and helped shape national security strategy across the Middle East.

Our conversation kicks off with Josh’s state of the venture industry and Lux’s positioning within it. Brett then describes his background, sovereign ambitions, and geopolitical risks. We discuss directional arrows of progress across AI, cap-ex maintenance, biology, defense systems, and space.